Comprehensive Literature Review: Recent Advances in Diagnosing and Managing Patients with Poorly Differentiated Thyroid Carcinoma

Background: Thyroid antibodies have a key role in follow up of the patients with thyroid carcinoma, thus present study investigates thyroid antibodies in patients with differentiated thyroid carcinoma. Material and Methods: For this cross sectional study, 157 patients with differentiated thyroid carcinoma (case group) and 434 healthy subjects (control group) were included. Serum level of antit...

آنتی‌بادی‌های تیروئید در بیماران با سرطان دیفرانسیه تیروئید در تهران

Background: Thyroid antibodies have a key role in follow up of the patients with thyroid carcinoma, thus present study investigates thyroid antibodies in patients with differentiated thyroid carcinoma. Material and Methods: For this cross sectional study, 157 patients with differentiated thyroid carcinoma (case group) and 434 healthy subjects (control group) were included. Serum level of antit...

Poorly Differentiated and Undifferentiated Thyroid Carcinomas.

Thyroid cancer is the most common endocrine malignancy and its incidence goes on increasing worldwide. The majority of thyroid tumours comprise well-differentiated (papillary and follicular) thyroid carcinomas that usually carry an excellent prognosis, while a minority progress to poorly differentiated carcinoma (PDTC) and, ultimately, to the highly aggressive and lethal undifferentiated carcin...

Evaluation of response to I-131 ablative therapy in patients with differentiated thyroid carcinoma: A five year retrospective study [Persian]

Differentiated thyroid carcinomas usually show good uptake and response to I-131 ablative treatment. In this study, 90 patients following near total thyroidectomy who were referred to our institute for I-131 therapy are retrospectively studied. The patients are divided in two groups. Group 1 revealed complete ablation after one dose of I-131. Group 2 needed more than one dose of I-131 for...

Resistance to Kinase Inhibitors in Poorly Differentiated and Anaplastic Thyroid Cancer: Preclinical In vitro Evidences

Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) are rare but highly aggressive malignancies with an extremely short survival. Poor prognosis is due to their unlimited growth, invasion, migration and resistance to common anticancer therapies. Advances in understanding the molecular alterations in thyroid carcinomas led to development of new therapeutic strategies ...